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Human neuroblastoma cells in culture: a model for neuronal cell differentiation and function
S Påhlman1, S Mamaeva, G Meyerson
1Department of Pathology, University Hospital, University of Uppsala, Sweden.
Acta Physiologica Scandinavica. Supplementum
|January 1, 1990
Abstract
None:
The human neuroblastoma cell line, SH-SY5Y, differentiates into neuron-like cells according to morphological, biochemical and functional criteria when treated with biologically active phorbol-esters. The differentiated phenotype is described and alterations in proto-oncogene expression in connection with growth control and differentiation are presented and discussed.