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Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...
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Updated: May 21, 2026

Gene Expression Profiling of Infecting Microbes Using a Digital Bar-coding Platform
09:13

Gene Expression Profiling of Infecting Microbes Using a Digital Bar-coding Platform

Published on: January 13, 2016

Gene expression in fungi.

Ayse Kalkanci1, Aras Kadioglu, Duncan Wilson

  • 1Gazi University Faculty of Medicine, Department of Medical Microbiology, Ankara, 06500 Turkey;

IMA Fungus
|June 9, 2012
PubMed
Summary
This summary is machine-generated.

This review covers gene expression in fungi, focusing on Candida albicans virulence, host adaptation, and azole susceptibility. It also discusses fungal gene transfer, evolution, and adaptation to environmental factors.

Keywords:
Candida albicansCryptococcus neoformansanimal modelsfungal adaptationgene transfervirulence genes

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Small-Scale Plasma Membrane Preparation for the Analysis of Candida albicans Cdr1-mGFPHis

Published on: June 13, 2021

Area of Science:

  • Mycology
  • Molecular Biology
  • Genetics

Background:

  • Fungal gene expression is crucial for understanding virulence and adaptation.
  • Candida albicans is a significant fungal pathogen requiring study.
  • Environmental adaptation and evolution are key aspects of fungal biology.

Purpose of the Study:

  • To summarize recent findings on fungal gene expression presented at IMC9.
  • To discuss virulence factors and host adaptation in Candida albicans.
  • To explore gene transfer, evolution, and environmental adaptation in fungi.

Main Methods:

  • Review of presentations from a Special Interest Group meeting on Gene Expression in Fungi.
  • Discussion of in vivo animal models for fungal virulence studies.
  • Analysis of gene expression data related to fungal adaptation and drug susceptibility.

Main Results:

  • Key genes associated with Candida albicans infection and host adaptation were identified.
  • Azole susceptibility in fungi is linked to alterations in specific gene expression patterns.
  • Fungal gene transfer contributes to evolution and adaptation to diverse environments.

Conclusions:

  • Understanding fungal gene expression is vital for controlling infections and predicting treatment outcomes.
  • Fungal adaptation mechanisms, including gene transfer, drive evolution and environmental resilience.
  • Further research into gene expression will illuminate fungal pathogenesis and evolution.