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Adaptive susceptibility shifts in Candidozyma auris following biocidal exposure: Exploratory effects on antifungal and biocidal susceptibility.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2026
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Meningitis caused by Candida dubliniensis in a patient with meningioma: a systematic review of the literature.

Irish journal of medical science·2026
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Impact of immune status on respiratory virus prevalence and co-detection patterns: a retrospective analysis (2019-2024).

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The Role of microRNAs and Cell-Free DNAs in Fungal Infections: Systematic Review and Meta-Analysis of the Literature.

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Minimum Inhibitory Concentrations of Anidulafungin as a Potential Predictor of Biocide Susceptibility of Clade 1 Candidozyma (Candida) auris Isolates.

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Biocide, antifungal susceptibility and virulence characteristics of Clade 1 Candidozyma auris strains.

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A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms
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Biocide Response of Candida auris.

Sidre Erganis1, Ali Ozturk2, Elif Ayca Sahin1

  • 1Faculty of Medicine Department of Medical Microbiology, Gazi University, Ankara, Türkiye.

Mycoses
|March 19, 2026
PubMed
Summary

Candida auris, a multidrug-resistant yeast, persists in healthcare settings. Effective control requires tailored disinfectant strategies, considering agent selection and environmental factors to prevent transmission.

Keywords:
Candida aurisbiocide activity testsbiocide tolerancechlorine‐based disinfectantsdisinfectant resistanceenvironmental persistenceinfection controlnosocomial transmissionquaternary ammonium compounds

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Area of Science:

  • Infectious Diseases
  • Microbiology
  • Environmental Health

Background:

  • Candida auris is a multidrug-resistant yeast causing healthcare-associated infections.
  • Its persistence in the environment facilitates nosocomial transmission and outbreaks.
  • Disinfectant failures highlight challenges in infection control.

Purpose of the Study:

  • To review the efficacy of common disinfectants against Candida auris.
  • To understand the mechanisms of C. auris tolerance to biocides.
  • To inform optimized infection prevention strategies.

Main Methods:

  • Literature review of experimental studies and environmental surveillance.
  • Analysis of comparative disinfection efficacy data.
  • Integration of mechanistic findings on biofilm and stress response.

Main Results:

  • Candida auris exhibits reduced susceptibility to quaternary ammonium compounds.
  • Variable, strain-dependent tolerance to alcohol disinfectants observed, especially with organic load.
  • Chlorine-based oxidizers effective at appropriate concentrations and contact times.
  • Biofilm formation increases persistence and reduces decontamination efficacy.

Conclusions:

  • Candida auris requires distinct disinfection strategies compared to other Candida species.
  • Optimized agent selection, contact times, and environmental conditions are crucial.
  • Tailored decontamination protocols are essential to limit spread in healthcare settings.