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Updated: May 21, 2026

Isolation, Behavioral Identification, and Pathogenicity Assessment of Entomopathogenic Fungi from a Forest Wood Borer
06:58

Isolation, Behavioral Identification, and Pathogenicity Assessment of Entomopathogenic Fungi from a Forest Wood Borer

Published on: September 29, 2023

Eumycetoma.

Roberto Estrada1, Guadalupe Chávez-López, Guadalupe Estrada-Chávez

  • 1Mycology-Dermatology Department, Hospital General de Acapulco/Medical School, Universidad Autónoma de Guerrero, Av. Ruiz Cortines No. 128, Col. Alta Progreso, Acapulco, Guerrero, Mexico. restrada_13@hotmail.com

Clinics in Dermatology
|June 12, 2012
PubMed
Summary
This summary is machine-generated.

Eumycetoma, a fungal infection, is diagnosed through microscopy and histology, with molecular methods aiding species identification. Optimal treatment combines surgical removal with antifungal medications like azoles, with newer agents recommended for resistant cases.

Related Experiment Videos

Last Updated: May 21, 2026

Isolation, Behavioral Identification, and Pathogenicity Assessment of Entomopathogenic Fungi from a Forest Wood Borer
06:58

Isolation, Behavioral Identification, and Pathogenicity Assessment of Entomopathogenic Fungi from a Forest Wood Borer

Published on: September 29, 2023

Area of Science:

  • Mycology
  • Infectious Diseases
  • Dermatology

Background:

  • Eumycetoma is a chronic subcutaneous infection caused by various fungi, commonly affecting the lower extremities.
  • Key causative agents include Madurella mycetomatis, Madurella grisae, and Scedosporium apiospermum.
  • Diagnosis relies on microscopic and histological examination for characteristic fungal hyphae and vesicles.

Purpose of the Study:

  • To review the diagnostic and therapeutic approaches for eumycetoma.
  • To highlight the challenges in etiologic identification and the evolving treatment strategies.

Main Methods:

  • Review of diagnostic techniques including direct microscopy, histology, and molecular methods for fungal identification.
  • Analysis of treatment outcomes with traditional and newer antifungal agents.

Main Results:

  • Fungal species identification can be challenging with conventional methods, necessitating molecular techniques.
  • Amphotericin B is rarely used due to side effects and limited efficacy.
  • Surgical excision combined with antifungal therapy is the preferred treatment approach.

Conclusions:

  • Effective management of eumycetoma requires accurate diagnosis, including species identification.
  • Current treatment emphasizes surgical intervention followed by azole antifungals (ketoconazole, itraconazole), with posaconazole and voriconazole for resistant infections.
  • Combination therapy, such as terbinafine and itraconazole, shows promise in select cases.