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Related Concept Videos

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...

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Related Experiment Video

Updated: May 21, 2026

Rapid Homogeneous Detection of Biological Assays Using Magnetic Modulation Biosensing System
06:58

Rapid Homogeneous Detection of Biological Assays Using Magnetic Modulation Biosensing System

Published on: June 13, 2010

On-chip bioanalysis with magnetic particles.

Nicole Pamme1

  • 1The University of Hull, Department of Chemistry, Hull HU6 7RX, UK. n.pamme@hull.ac.uk

Current Opinion in Chemical Biology
|June 12, 2012
PubMed
Summary
This summary is machine-generated.

Magnetic particles offer dual selectivity for bioanalysis, enabling molecular recognition and easy isolation. Recent advancements showcase their use in lab-on-a-chip systems, continuous flow assays, and rapid cell sorting.

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Last Updated: May 21, 2026

Rapid Homogeneous Detection of Biological Assays Using Magnetic Modulation Biosensing System
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Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
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Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

Area of Science:

  • Biotechnology
  • Analytical Chemistry
  • Materials Science

Background:

  • Magnetic particles combine molecular recognition for analyte binding with physical isolation from complex mixtures.
  • Applications span cell isolation, immunoassays, and DNA extraction.

Purpose of the Study:

  • To review recent trends and advancements in the application of magnetic particles in bioanalysis.
  • To highlight the integration of magnetic particles in lab-on-a-chip systems and continuous flow processes.

Main Methods:

  • Review of recent literature on magnetic particle applications in bioanalysis.
  • Focus on on-particle processing in continuous flow systems.
  • Discussion of droplet manipulation and cell sorting techniques using magnetic particles.

Main Results:

  • Magnetic particles are integral to integrated sample-in-answer-out lab-on-a-chip systems.
  • On-particle processing in continuous flow has been demonstrated for assays and DNA extraction.
  • Advancements in magnet configurations enable rapid sorting of magnetically labeled cells.

Conclusions:

  • Magnetic particles are versatile tools in modern bioanalysis, particularly in microfluidic and automated systems.
  • Ongoing improvements in magnetic particle technology are expanding their capabilities in complex biological sample processing and analysis.