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Updated: May 21, 2026
07:49
Conventional BODIPY Conjugates for Live-Cell Super-Resolution Microscopy and Single-Molecule Tracking
Published on: June 8, 2020
DNA polyfluorophores for real-time multicolor tracking of dynamic biological systems
Shenliang Wang1, Jia Guo, Toshikazu Ono
1Department of Chemistry, Stanford University, Stanford, CA 94305, USA.
Angewandte Chemie (International Ed. in English)
|June 12, 2012
Abstract:
Dye-ing to live: Spectral limitations of common organic dyes make it difficult or impossible to visualize and follow multiple biological components in rapidly moving systems. The development of a multispectral set of improved DNA-scaffolded fluorophores is described. Their use in multicolor cellular imaging (see scheme) and in tracking of biological motions on the subsecond timescale is demonstrated.
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