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Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
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Updated: May 21, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

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Published on: June 23, 2023

Problem based review: alcohol-use disorders on the Acute Medical Unit.

Toby Reynolds1, Fiona Cooke, Nick Murch

  • 1Acute Medicine, Royal London Hospital, UK.

Acute Medicine
|June 12, 2012
PubMed
Summary
This summary is machine-generated.

Acute physicians must manage alcohol-use disorders, recognizing inpatient detoxification needs and community-based options. Brief interventions benefit higher-risk drinkers, while Wernicke

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Area of Science:

  • Internal Medicine
  • Addiction Medicine
  • Emergency Medicine

Background:

  • Alcohol-use disorders (AUDs) are prevalent in acute medical settings.
  • Management requires awareness of intoxication and withdrawal syndromes.

Observation:

  • Acute physicians encounter patients with diverse alcohol-related conditions.
  • Higher-risk drinkers may benefit from early intervention.
  • Confusion and malnutrition in high-intake patients suggest Wernicke's Encephalopathy.

Findings:

  • Inpatient detoxification indications must be recognized.
  • Collaboration with specialist alcohol services is crucial for community detoxification planning.
  • Brief Interventions are effective for non-dependent, higher-risk drinkers.
  • Parenteral thiamine is essential for suspected Wernicke's Encephalopathy.

Implications:

  • Optimizing acute care for alcohol-use disorders improves patient outcomes.
  • Integrated care pathways enhance management of alcohol-related conditions.
  • Early identification and intervention reduce long-term harm from alcohol misuse.