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Updated: May 21, 2026

Stenosis of the Inferior Vena Cava: A Murine Model of Deep Vein Thrombosis
Published on: December 22, 2017
A case of mediastinal seminoma presenting as superior vena cava syndrome
Xue Xu1, Chengtao Sun, Lei Zhang
1Shandong Province Qianfoshan Hospital, Shandong University, Shandong 250014, China.
Abstract:
Primary mediastinal seminoma is a rare tumor usually with nonspecific symptoms such as chest pain, dyspnea and hoarseness, but superior vena cava syndrome (SVCS) is an extremely uncommon syndrome. We report a 25-year-old man who presented with superior vena cava syndrome for 1 month and a 1-week history of retrosternal chest pain. Thorax computerized tomography demonstrated a soft tissue mass in the anterior mediastinum with stippled calcifications compressing the superior vena cava and other major vessels. Transthoracic biopsy showed primary seminoma of the anterior mediastinum. Combined chemoradiotherapy was performed and the patient was considered to have a partial response to treatment.
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