[Risk factors for metabolic syndrome in a case control study in Temuco, Chile]
Patricia Philco L1, Pamela Serón S, Sergio Muñoz N
1Facultad de Medicina, Centro de Excelencia en Capacitación, Investigación y Gestión para la Salud Basada en Evidencia, Universidad de la Frontera, Chile. patricia_philco@yahoo.com
Revista Medica De Chile
|June 13, 2012
Summary
Metabolic syndrome risk factors in Southern Chile include Mapuche origin, family history of diabetes, and depression. Regular wine consumption showed a protective effect, particularly in older adults.
Area of Science:
- Public Health
- Epidemiology
- Cardiovascular Health
Background:
- Metabolic syndrome is a growing public health concern in developed nations.
- Identifying regional risk factors is crucial for targeted interventions.
Purpose of the Study:
- To investigate factors associated with metabolic syndrome in Southern Chile.
- To compare individuals with and without metabolic syndrome.
Main Methods:
- Case-control study with 400 participants (200 cases, 200 controls) aged 35-70.
- Data collected on ethnicity, lifestyle, medical history, and diet.
- Metabolic syndrome defined by National Cholesterol Education Program (NCEP_ATPIII) criteria.
Main Results:
- Mapuche origin, family history of diabetes, and depression were significant risk factors.
- Increased BMI change and age over 54 were also associated with higher risk.
- Moderate wine consumption was a protective factor, especially in older individuals.
Conclusions:
- Key risk factors for metabolic syndrome in this population are Mapuche ethnicity, family diabetes history, and depression.
- Lifestyle factors and age are important considerations.
- Wine consumption may offer a protective benefit against metabolic syndrome.
Related Concept Videos
01:26Type II Diabetes I: Introduction
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
01:30Coronary Artery Disease I: Introduction
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
01:29Cholesterol: Significance and Regulation
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Considering cholesterol and...
01:20Cholecystitis
Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
01:24Type II Diabetes II: Pathophysiology
PathophysiologyType 2 diabetes mellitus (T2DM ) is a chronic metabolic disorder characterized by insulin resistance and progressive pancreatic β-cell dysfunction, leading to impaired glucose homeostasis. It results from interactions among genetic predisposition, environmental factors, and metabolic stressors, such as overnutrition and a sedentary lifestyle.Insulin Resistance and Glucose DysregulationEarly T2DM involves insulin resistance in skeletal muscle, adipose tissue, and the liver.
01:27Psychoneuroimmunology: Cardiovascular Disease
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...