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Strange taste and mild lithium intoxication.

Takeshi Terao¹, Shosuke Watanabe, Nobuhiko Hoaki

¹Oita University Faculty of Medicine, Oita, Japan. terao@oita-u.ac.jp

BMJ Case Reports

|June 13, 2012

Summary

Lithium medication can cause taste changes, a potential side effect not widely recognized. These taste alterations may indicate mild lithium intoxication, resolving upon dose adjustment or discontinuation.

Area of Science:

Neuroscience
Pharmacology
Psychiatry

Background:

Lithium is a widely prescribed mood stabilizer for bipolar disorder.
Adverse effects of lithium are well-documented, but taste disturbances are infrequently reported.

Observation:

A 61-year-old bipolar disorder patient reported experiencing significant taste changes.
These taste alterations coincided with an increase in lithium dosage, reaching 1.28 mEq/L.

Findings:

The patient's taste perception returned to normal after discontinuing lithium treatment.
This suggests a direct correlation between lithium levels and taste disturbances.

Implications:

Taste alteration may serve as an early indicator of lithium toxicity.

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Clinicians should consider monitoring for taste changes in patients treated with lithium.

Further research is warranted to elucidate the mechanism of lithium-induced taste alterations.