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Characterization of three new HLA-B alleles: B*35:05:03, B*52:29 and B*57:01:13

W T N Swelsen1, K S Hartog, B Poell

  • 1Department of Immunogenetics, Sanquin Blood Supply Foundation, Amsterdam, The Netherlands.

Tissue Antigens
|June 14, 2012
PubMed

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Blood Types02:20

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Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
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An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
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