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Updated: May 21, 2026

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
Published on: June 1, 2019
Schmorl's node mimicking metastasis in a patient with breast cancer: diagnosis with 99mTC methylene diphosphonate
Harmandeep Singh1, Punit Sharma, Niraj Naswa
1Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Abstract:
Schmorl's node (SN) is a common entity characterized by protrusion of intervertebral disc material through a break in the subchondral end plate of a vertebral body. They can show increased 99mTC methylene diphosphonate uptake on bone scintigraphy mimicking metastasis and can be symptomatic. Differentiation of SN from metastasis is essential for appropriate patient management. Here, we present a case where increased 99mTC methylene diphosphonate uptake in a dorsal vertebra was found to be because of SN by using single-photon emission computed tomography-computed tomography.
