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Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays
Published on: June 23, 2022
A rapid and facile signal enhancement method for microcantilever-based immunoassays using the agglomeration of
Dongkyu Lee1, Donghoon Kwon, Wooree Ko
1Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, Korea.
Chemical Communications (Cambridge, England)
|June 14, 2012
Abstract:
A rapid and facile signal enhancement method for detecting alpha-fetoprotein (AFP) was developed using the magnetic agglomeration of ferromagnetic nanoparticles and microcantilever sensors. The resonance frequency and deflection of the cantilevers were found to be more than 10-fold greater than that before physical agglomeration of the free nanoparticles around the magnetized nanoparticles.
