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Updated: May 21, 2026

In Situ Immunofluorescent Staining of Autophagy in Muscle Stem Cells
Published on: June 12, 2017
Emerging role of autophagy in kidney function, diseases and aging
Tobias B Huber1, Charles L Edelstein, Björn Hartleben
1Renal Division, University Hospital Freiburg; Freiburg, Germany. tobias.huber@uniklinik-freiburg.de
Abstract:
Autophagy is a highly conserved process that degrades cellular long-lived proteins and organelles. Accumulating evidence indicates that autophagy plays a critical role in kidney maintenance, diseases and aging. Ischemic, toxic, immunological, and oxidative insults can cause an induction of autophagy in renal epithelial cells modifying the course of various kidney diseases. This review summarizes recent insights on the role of autophagy in kidney physiology and diseases alluding to possible novel intervention strategies for treating specific kidney disorders by modifying autophagy.
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