Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Calculating excess lifetime risk in relative risk models.

M Vaeth1, D A Pierce

  • 1Aarhus Universitet, Afdeling for Teoretisk Statistik, Denmark.

Environmental Health Perspectives
|July 1, 1990
PubMed
Summary

This study introduces a simplified method for estimating excess lifetime cancer risk from radiation exposure. The approximation is validated for low doses, aiding in understanding risk projection factors and uncertainties.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reduced mesiodistal tooth dimension in individuals with osteogenesis imperfecta: a cross-sectional study.

Acta odontologica Scandinavica·2020
Same author

Preferred Reporting items for OBservational studies in Endodontics (PROBE) guidelines: a development protocol.

International endodontic journal·2020
Same author

PRIRATE 2020 guidelines for reporting randomized trials in Endodontics: a consensus-based development.

International endodontic journal·2020
Same author

Diagnostic accuracy of cone beam computed tomography used for assessment of apical periodontitis: an ex vivo histopathological study on human cadavers.

International endodontic journal·2018
Same author

Impact of cone beam computed tomography on periapical assessment and treatment planning five to eleven years after surgical endodontic retreatment.

International endodontic journal·2018
Same author

Prediction of periapical status and tooth extraction.

International endodontic journal·2015

Area of Science:

  • Radiation epidemiology
  • Risk assessment
  • Biostatistics

Background:

  • Assessing radiation exposure impact commonly involves excess lifetime cancer risk.
  • Current methods for risk projection have significant uncertainties and complexities.

Purpose of the Study:

  • To address methodological issues in calculating excess lifetime cancer risk.
  • To propose and validate a simplified approximation for excess lifetime risk estimation.
  • To explore factors influencing radiation risk projections.

Main Methods:

  • Utilized the age-constant relative risk model from Hiroshima and Nagasaki A-bomb survivor data.
  • Developed and empirically/theoretically justified a simple approximation for excess lifetime risk.
  • Analyzed the influence of latent periods, site-specific risks, and population transfer.

Main Results:

  • A validated, simple approximation for excess lifetime cancer risk at low exposure levels was developed.
  • The approximation offers insights into factors affecting risk projections.
  • Identified uncertainties in transferring risk data between populations.

Conclusions:

  • The proposed approximation simplifies excess lifetime cancer risk calculations, particularly for low-dose exposures.
  • This method aids in understanding radiation risk projection complexities.
  • Highlights the need to address uncertainties in radiation risk assessment and transfer.

Related Experiment Videos