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Sporotrichosis in Nepal
C Rajendran1, V Ramesh, R S Misra
1Medical Mycology Laboratory, National Institute of Communicable Diseases, Delhi, India.
International Journal of Dermatology
|December 1, 1990
Summary
The first reported case of sporotrichosis in Nepal involved a man who contracted the lymphocutaneous form after a foot injury. Treatment with oral potassium iodide led to a full recovery.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Tropical Medicine
Background:
- Sporotrichosis is a fungal infection typically caused by Sporothrix schenckii.
- It commonly affects the skin and lymphatic system, often following minor trauma.
- Geographic distribution and incidence vary, with limited data from certain regions like Nepal.
Observation:
- A 25-year-old Nepalese man presented with the lymphocutaneous form of sporotrichosis.
- The infection was acquired following an injury to his right foot while cutting wood.
- He had no history of travel outside Nepal.
Findings:
- Diagnosis was confirmed by culturing Sporothrix schenckii from lesion samples.
- In vitro studies demonstrated the fungus's dimorphic nature.
- Pathogenicity was confirmed in mouse models, and serological tests were positive.
Implications:
- This case represents the first documented instance of sporotrichosis in Nepal.
- It highlights the potential for Sporothrix schenckii to cause infection in previously unreported regions.
- Successful treatment with oral potassium iodide demonstrates a viable therapeutic option for this mycosis.