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Updated: May 21, 2026

Phase-Resolved Functional Lung MRI for Pulmonary Ventilation and Perfusion (V/Q) Assessment
Published on: August 9, 2024
MRI of the lung (1/3): methods
1Academic Radiology, Royal Hallamshire Hospital Sheffield, University of Sheffield, Sheffield, S10 2JF, UK, j.m.wild@sheffield.ac.uk.
Abstract:
Proton magnetic resonance imaging (MRI) has recently emerged as a clinical tool to image the lungs. This paper outlines the current technical aspects of MRI pulse sequences, radiofrequency (RF) coils and MRI system requirements needed for imaging the pulmonary parenchyma and vasculature. Lung MRI techniques are presented as a "technical toolkit", from which MR protocols will be composed in the subsequent papers for comprehensive imaging of lung disease and function (parts 2 and 3). This paper is pitched at MR scientists, technicians and radiologists who are interested in understanding and establishing lung MRI methods. Images from a 1.5 T scanner are used for illustration of the sequences and methods that are highlighted. Main Messages • Outline of the hardware and pulse sequence requirements for proton lung MRI • Overview of pulse sequences for lung parenchyma, vascular and functional imaging with protons • Demonstration of the pulse-sequence building blocks for clinical lung MRI protocols.
Insights
Proton magnetic resonance imaging (MRI) offers a new way to visualize the lungs. This paper details the essential technical components and pulse sequences for establishing effective lung MRI protocols.
Area of Science:
- Medical Imaging
- Radiology
- Biophysics
Background:
- Proton magnetic resonance imaging (MRI) is a developing clinical method for lung visualization.
- Understanding the technical requirements is crucial for implementing lung MRI.
Purpose of the Study:
- To outline the technical aspects of proton MRI for lung imaging.
- To present a toolkit of MRI pulse sequences, radiofrequency (RF) coils, and system requirements.
- To serve as a foundation for future papers on lung disease and function imaging.
Main Methods:
- Detailed review of MRI hardware, including radiofrequency (RF) coils and system specifications.
- Explanation of various MRI pulse sequences applicable to lung parenchyma, vasculature, and functional imaging.
- Illustration of pulse-sequence building blocks for constructing clinical lung MRI protocols using a 1.5 T scanner.
Main Results:
- Established the necessary hardware and pulse sequence requirements for proton lung MRI.
- Provided an overview of pulse sequences suitable for lung parenchyma, vascular, and functional imaging.
- Demonstrated the fundamental components for developing clinical lung MRI protocols.
Conclusions:
- Proton lung MRI requires specific technical considerations for hardware and pulse sequences.
- A foundational understanding of these elements is key to establishing robust clinical protocols.
- This work provides essential technical guidance for MR scientists, technicians, and radiologists.
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