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Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...

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Related Experiment Video

Updated: May 21, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
09:42

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Published on: August 26, 2014

Small bowel MR enterography: problem solving in Crohn's disease.

Nyree Griffin1, Lee Alexander Grant, Simon Anderson

  • 1Department of Radiology, Guy's & St Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, UK, nyreegriffin100@gmail.com.

Insights Into Imaging
|June 15, 2012
PubMed
Summary

Magnetic resonance enterography (MRE) is the preferred imaging technique for Crohn's disease, offering detailed visualization of complications without radiation. MRE aids in assessing disease activity and differentiating between inflammatory, stricturing, and penetrating conditions.

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Murine Ileocolic Bowel Resection with Primary Anastomosis
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Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

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Last Updated: May 21, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
09:42

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Published on: August 26, 2014

Murine Ileocolic Bowel Resection with Primary Anastomosis
08:49

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

Area of Science:

  • Radiology
  • Gastroenterology
  • Medical Imaging

Background:

  • Crohn's disease management requires accurate small bowel evaluation.
  • Magnetic resonance enterography (MRE) is emerging as a primary radiological tool for assessing Crohn's disease.
  • MRE offers advantages like no ionizing radiation and superior contrast resolution.

Purpose of the Study:

  • To detail the MRE protocol and sequence rationale for Crohn's disease evaluation.
  • To compare MRE with alternative small bowel imaging modalities.
  • To illustrate MRE's utility in distinguishing disease types and complications.

Main Methods:

  • Utilizing T2-weighted, post-contrast, and diffusion-weighted imaging (DWI) sequences.
  • Implementing a standardized MRE protocol for small bowel assessment.
  • Reviewing MRE findings in the context of Crohn's disease pathology.

Main Results:

  • MRE effectively demonstrates both mural and extramural complications in Crohn's disease.
  • The technique aids in assessing disease activity, a critical factor in patient management.
  • MRE distinguishes between inflammatory, stricturing, and penetrating disease patterns.

Conclusions:

  • MRE is a valuable, non-invasive imaging modality for Crohn's disease assessment.
  • Its multiplanar and cine capabilities enhance diagnostic accuracy.
  • MRE facilitates tailored management strategies by characterizing disease behavior.