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Updated: May 21, 2026

Assessment of Myofilament Ca2+ Sensitivity Underlying Cardiac Excitation-contraction Coupling
Published on: August 1, 2016
The physiology of cardiac calcium handling
Nils Bögeholz1, Adam Muszynski, Christian Pott
1Division of Clinical and Experimental Rhythmology, Department of Cardiology and Angiology, University Hospital Münster, Münster, Germany. nils.boegeholz@googlemail.com
Abstract:
Cardiac calcium (Ca(2+)) handling subsumes the mechanisms maintaining the myocardial Ca(2+) homeostasis that contribute essentially to cardiac performance. This review addresses the interaction of transplasmalemmal and transsarcoplasmic Ca(2+) flux, its potential modifications due to β-adrenergic stimulation and its implications on cardiac action potential.
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