A structurally informed autotransporter platform for efficient heterologous protein secretion and display

Wouter S P Jong1, Zora Soprova, Karin de Punder

  • 1Section Molecular Microbiology, Department of Molecular Cell Biology, Faculty of Earth and Life Sciences, VU University, De Boelelaan 1085, 1081 HV, Amsterdam, The Netherlands. w.s.p.jong@vu.nl

Summary

Researchers engineered the Hemoglobin protease (Hbp) autotransporter (AT) platform for efficient secretion and surface display of heterologous proteins, showing potential for recombinant live vaccines and biotechnology.

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