Related Experiment Video
Updated: May 21, 2026

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
Published on: December 5, 2025
Recruitment maneuver in prevention of hypoxia during percutaneous dilational tracheostomy: randomized trial
Federico Franchi1, Lucia Cubattoli, Agnese Faltoni
1Department of Anesthesia and Intensive Care, University of Siena, Siena, Italy. franchif@unisi.it
Background:
Percutaneous dilational tracheostomy (PDT) can potentially lead to hypoxia and alveolar derecruitment. The aim of this prospective study was to evaluate the efficacy of performing a recruitment maneuver (RM) before tracheostomy, in order to improve oxygenation.
Methods:
We enrolled 29 eligible trauma patients with acute lung injury criteria requiring tracheostomy in a university ICU. Subjects were ventilated on volume controlled mechanical ventilation (tidal volume of 6 mL/kg) and F(IO(2)) set at 1.0. Subjects were randomized into 2 groups: RM group (subjects who underwent RM 10 min before PDT, 15 subjects) and no-RM group (subjects without application of RM before PDT, 14 subjects). RM was performed by imposition of continuous positive airway pressure of 40 cm H(2)O for 40 seconds. We collected gas exchange, respiratory, and hemodynamic data 5 times: 1 hour before RM, 5 min after RM, 5 min after PDT, 30 min after PDT, and 6 hours after PDT.
Results:
Subjects who underwent RM had a significant increase in P(aO(2)); 5 min after the maneuver, P(aO(2)) increased from 222.6 ± 33.4 mm Hg to 341.3 ± 33.1 mm Hg (P < .01) and was always significantly maintained throughout the following times of the study, compared to the no-RM group: in the RM and no-RM groups, respectively, 260.7 ± 35.4 mm Hg vs 108.5 ± 36.9 mm Hg 5 min after PDT; 285.6 ± 29.1 mm Hg vs 188.4 ± 21.4 mm Hg 30 min after PDT; and 226.3 ± 24.8 mm Hg vs 147.6 ± 42.8 mm Hg 6 h after PDT (P < .01).
Conclusions:
Our study suggests that application of RM before PDT could be useful to avoid hypoxemia following such procedure, by reducing fall in P(aO(2)) and preventing the decrease in oxygenation values below baseline at 6 hours.
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