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Updated: May 21, 2026
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Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Management of hemorrhage from cavernous malformations
Sachin Batra1, Karen Rigamonti, Daniele Rigamonti
1University of Texas Medical School at Houston, 77630, USA.
Current Atherosclerosis Reports
|June 20, 2012
Summary
Cavernous malformations (CMs) often follow a benign course and usually require conservative management. Treatment decisions for deep or inaccessible CMs should consider that surgical or radiosurgical outcomes may not surpass conservative approaches.
Area of Science:
- Vascular Neurology
- Neurosurgery
- Radiosurgery
Background:
- Cavernous malformations (CMs) are vascular anomalies composed of endothelium-lined sinusoids.
- Most CMs are asymptomatic and incidentally discovered.
- The natural history of CMs is generally considered benign.
Purpose of the Study:
- To review the natural history of cavernous malformations.
- To evaluate outcomes of conservative management, surgery, and radiosurgery for CMs.
- To inform individualized treatment strategies for patients with CMs.
Main Methods:
- Review of existing literature on cavernous malformation natural history and treatment outcomes.
- Analysis of conservative management, surgical resection, and radiosurgical treatment approaches.
- Synthesis of data to compare efficacy and patient outcomes across different treatment modalities.
Main Results:
- Conservative management is often suitable for the majority of CM cases.
- Treatment consensus for deep or inaccessible CMs is lacking, with a trend towards radiosurgery.
- Outcomes from surgical or radiosurgical interventions have not consistently demonstrated superiority over conservative management.
Conclusions:
- Understanding the natural history of CMs is crucial for patient care.
- Individualized treatment strategies should be developed based on lesion characteristics and patient goals.
- Further research is needed to establish optimal management protocols for complex CM cases.
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