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Intrauterine Drug Delivery Systems01:21

Intrauterine Drug Delivery Systems

Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
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Related Experiment Video

Updated: May 21, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
09:51

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

Delivery of twins.

Young Mi Lee1

  • 1Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Weill Cornell Medical College, New York, NY 10065, USA. YML9002@med.cornell.edu

Seminars in Perinatology
|June 21, 2012
PubMed
Summary
This summary is machine-generated.

Optimal management for twin pregnancies varies by chorionicity and amnionicity. Recommendations include specific gestational ages for delivery and considerations for vaginal birth versus Cesarean delivery based on fetal presentation and risk factors.

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Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
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Last Updated: May 21, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
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Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
09:04

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas

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Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
09:52

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye

Published on: September 5, 2011

Area of Science:

  • Maternal-Fetal Medicine
  • Obstetrics
  • Perinatology

Background:

  • Twin gestations present unique management challenges compared to singleton pregnancies.
  • Evidence-based guidelines for optimal timing and mode of delivery in twin pregnancies are limited.
  • Chorionicity and amnionicity significantly influence pregnancy outcomes and management strategies.

Purpose of the Study:

  • To review current literature on the management of twin gestations.
  • To discuss optimal gestational age for delivery in various twin types.
  • To outline considerations for the route of delivery in twin pregnancies.

Main Methods:

  • Literature review of current information on twin gestation management.
  • Analysis of data regarding optimal timing and mode of delivery.
  • Synthesis of recommendations based on chorionicity, amnionicity, and fetal presentation.

Main Results:

  • Recommended gestational ages: 38 weeks (dichorionic diamniotic), 34-36 weeks (monochorionic diamniotic), 32-34 weeks (monoamniotic).
  • Vaginal delivery may be considered for cephalic-cephalic twins and select cephalic-noncephalic presentations.
  • Cesarean delivery is recommended for monoamniotic twins, noncephalic presentations, and high-risk cases.

Conclusions:

  • Optimal management of twin deliveries is multifactorial and often debated.
  • Timing and mode of delivery decisions depend on chorionicity, amnionicity, provider expertise, and fetal presentation.
  • Individualized management plans are crucial for optimizing outcomes in twin gestations.