Related Experiment Video
Updated: May 21, 2026
08:06
Mixed Reality Assisted Radical Endoscopic Thyroidectomy
Published on: January 31, 2025
Factors influencing thyroidectomy complications
Miguel Ernandes-Neto1, José Vicente Tagliarini, Bárbara Estefania López
1Department of Pathology, Faculty of Medicine, Medical School of Botucatu, University of Sao Paulo, SP, Brazil. m_ernandes@yahoo.com.br
Brazilian Journal of Otorhinolaryngology
|June 21, 2012
Summary
Thyroidectomy complications, including vocal cord paralysis and hypoparathyroidism, were linked to factors like malignancy and surgical extent. Disease recurrence and persistence were associated with surgical timing and patient age.
Area of Science:
- Endocrinology
- Surgical Oncology
- Otolaryngology
Background:
- Thyroidectomy outcomes depend on patient, disease, and surgeon factors.
- Understanding complication predictors is crucial for improving thyroidectomy results.
Purpose of the Study:
- To analyze thyroidectomy complications and disease recurrence/persistence at a specific clinic.
- To identify clinical and laboratory factors associated with adverse outcomes.
Main Methods:
- Historical cross-sectional cohort study.
- Reviewed charts of 228 patients undergoing thyroidectomy between 1991 and 2004.
- Analyzed transient, permanent, total complications, persistence, and recurrence rates.
Main Results:
- Total complications occurred in 34.65%; permanent complications (hypoparathyroidism, vocal cord paralysis) in 17.98%.
- Complications linked to malignancy and radical surgeries.
- Disease persistence (17.98%) associated with older age; recurrence (10.96%) with earlier surgeries and benign disease.
Conclusions:
- Thyroidectomy complications are associated with pressure symptoms, malignancy, and surgical radicality.
- Disease recurrence is linked to initial surgical timing and benign thyroid conditions.
- Disease persistence is associated with patient age.
Related Concept Videos
01:27Hyperthyroidism II: Pathophysiology
Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...
01:24Graves Disease II: Pathophysiology
Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...
01:25Hyperthyroidism I: Introduction
Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
01:28Graves' Disease I: Introduction
Graves' disease is an autoimmune disorder that causes hyperthyroidism, or overactivity of the thyroid gland. It results from autoantibodies called thyroid-stimulating immunoglobulins (TSIs), which bind to thyroid-stimulating hormone (TSH) receptors, leading to overstimulation of hormone production and a hypermetabolic state.EtiologyAlthough considered idiopathic, Graves’ disease has well-established contributing factors. There is a strong genetic component, with increased prevalence in...
01:23Hypothyroidism II: Pathophysiology
Hypothyroidism is a disorder characterized by insufficient production of thyroid hormones, which regulate metabolism, energy balance, and multiple organ systems.TypesHypothyroidism is classified based on the level of dysfunction. Primary hypothyroidism results from intrinsic thyroid gland dysfunction, causing reduced hormone production despite normal or increased stimulation. Secondary hypothyroidism arises from inadequate thyroid-stimulating hormone (TSH) secretion by the pituitary. Tertiary...
01:23The Thyroid Gland
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...