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Association between Occupational High-Temperature Exposure and the Biological Aging of Workers
Yan Guo1, Rui Zhao2, Wei Chao Wu3
1Department of Biostatistics and Epidemiology, School of Public Health, Shenzhen University Medical School, Shenzhen 518060, Guangdong, China;Department of Labor Health and Occupational Diseases, School of Public Health, Zhengzhou University, Zhengzhou 450001, Henan, China.
Occupational high-temperature exposure significantly accelerates biological aging (BA) and organ-specific BA. High-temperature exposure and BMI interact to influence BA acceleration, with high temperatures, BMI, and smoking being risk factors.
Area of Science:
- Occupational Health
- Gerontology
- Biomarkers of Aging
Background:
- Biological aging is influenced by various environmental and lifestyle factors.
- Occupational exposure to high temperatures is a growing concern in industrial settings.
- Understanding the impact of occupational hazards on aging is crucial for public health.
Purpose of the Study:
- To investigate the association between occupational high-temperature exposure and accelerated biological aging.
- To determine the influence of factors like BMI, smoking, and sleep on biological age acceleration.
Main Methods:
- A study involving 140 male workers exposed to high temperatures and 207 controls.
- Biological age (BA) and organ-specific BA calculated using the Klemera-Doubal method.
- Generalized linear models used to analyze risk factors for BA acceleration.
Main Results:
- Workers exposed to high temperatures showed significantly accelerated biological aging (BA) and liver-kidney BA.
- High-temperature exposure, BMI, and smoking were identified as risk factors for BA acceleration.
- Sleep duration was found to be a protective factor against BA acceleration.
Conclusions:
- Occupational high-temperature exposure is linked to accelerated biological aging.
- An interaction between high-temperature exposure and BMI significantly affects biological age acceleration.
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