NOS-2 signaling and cancer therapy

Ka Bian1, Farshid Ghassemi, Alex Sotolongo

  • 1Department of Biochemistry and Molecular Biology, George Washington University, School of Medicine, Washington, DC, USA. bcmfxm@gwu.edu

IUBMB Life
|June 21, 2012
PubMed
Summary

Nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) signaling roles in cancer remain unclear. Targeting inducible nitric-oxide synthase (iNOS) and normalizing sGC-cGMP pathways may offer novel cancer therapies.

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