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[Vitamin D and neurological diseases]
Jirí Polívka1, Jirí Polívka, M Peterka
1Neurologická klinika Lékarské fakulty UK a FN Plzen. polivka@fnplzen.cz
Insights
Low vitamin D levels (hypovitaminosis) are linked to neurological conditions like cerebrovascular diseases and multiple sclerosis. This deficiency may directly impact disease risk and worsen functional outcomes in patients.
Area of Science:
- Neurology
- Endocrinology
- Public Health
Context:
- Growing evidence suggests a link between vitamin D deficiency and neurological disorders.
- Cerebrovascular diseases, multiple sclerosis, and cognitive disorders are frequently associated with low vitamin D.
- Vitamin D hypovitaminosis may influence disease pathogenesis and progression.
Purpose:
- To review the association between vitamin D and key neurological diseases.
- To explore the potential role of vitamin D deficiency in disease risk factors and functional status.
Summary:
- Vitamin D hypovitaminosis is correlated with cerebrovascular diseases, multiple sclerosis, and cognitive disorders.
- Deficiency may contribute to disease development or exacerbate risk factors, particularly for cerebrovascular events.
- Low vitamin D can negatively impact functional status, leading to muscle weakness, instability, and falls in neurological patients.
Impact:
- Highlights the importance of vitamin D status in neurological health.
- Suggests potential therapeutic targets for managing neurological diseases.
- Underscores the need for further research into vitamin D's role in preventing and treating neurological conditions.
Abstract:
We provide an overview of the association between vitamin D and some neurological diseases where the correlation has repeatedly been described. The majority of literature refers to cerebrovascular diseases, followed by multiple sclerosis and cognitive disorders. Vitamin D hypovitaminosis might be associated with the diseases directly or it might contribute to the disease risk factors (typically in cerebrovascular events). Vitamin D hypovitaminosis may also play a role in patients with residual functional involvement due to a neurological disorder (movement disorders, lack of self-sufficiency) and worsen functional status owing to muscle weakness, instability and falls.
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