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Updated: May 21, 2026

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Non-Intubated Video-Assisted Thoracoscopic Surgery
Published on: May 26, 2023
Subcutaneous botulinum toxin for chronic post-thoracotomy pain
Gustavo Fabregat1, Juan M Asensio-Samper, Stefano Palmisani
1Department of Multidisciplinary Pain Management, General University Hospital, Valencia, Spain. gfabregat@gmail.com
Summary
Botulinum toxin injections effectively treated chronic neuropathic pain following thoracotomy surgery. This neurotoxin offers a promising therapeutic option for localized pain refractory to conventional treatments.
Area of Science:
- Neurology
- Pain Management
- Pharmacology
Background:
- Botulinum toxin is a neurotoxin utilized for conditions involving localized muscle spasms.
- Emerging evidence indicates its efficacy in managing neuropathic pain, including post-herpetic neuralgia.
Observation:
- A 67-year-old male patient experienced persistent neuropathic pain along a thoracotomy scar for two years post-surgery.
- Standard pain treatments were ineffective for this refractory post-thoracotomy pain.
Findings:
- Subcutaneous injections of botulinum toxin type A provided successful pain relief.
- Fractionated subcutaneous administration of botulinum toxin may benefit various chronic localized pain conditions.
Implications:
- Botulinum toxin represents a viable treatment for chronic post-thoracotomy pain.
- This approach may extend to other localized neuropathic pain syndromes.
- Further research into fractionated botulinum toxin injections for chronic pain is warranted.
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