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Personal computer interface and software for the ZONAX microscope attachment controller.

D R Rigney1, J H Velyvis, J Y Wei

  • 1Harvard Medical School, Department of Medicine, Boston, Massachusetts.

Cytometry
|January 1, 1990
PubMed
Summary
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This study introduces a PC-based interface for controlling microscope-attached cytometric devices. It details converting the ZONAX controller for enhanced, personal computer-driven operation.

Area of Science:

  • Microscopy and Cytometry
  • Computer Hardware and Software Engineering
  • Biomedical Instrumentation

Background:

  • Microscope-attached cytometric devices traditionally required specialized hardware controllers.
  • Existing control systems, like the 8080-based ZONAX controller, lacked modern PC integration.
  • Seamless integration of computational power with optical microscopy is crucial for advanced research.

Purpose of the Study:

  • To present a versatile hardware and software interface for personal computer (PC) control of cytometric devices.
  • To demonstrate the conversion of an existing 8080-based ZONAX microscope attachment controller to PC-based control.
  • To enable enhanced automation and data acquisition in microscopy through PC integration.

Main Methods:

  • Development of a general-purpose interface connecting a PC running MS-DOS to cytometric peripherals.

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  • Integration of control for components such as scanning stages, shutters, and focus motors.
  • Modification of the ZONAX controller's architecture from 8080-based hardware to PC-driven operation.

    • Main Results:

    • Successful implementation of a PC-based control system for microscope-attached cytometric devices.
    • Demonstration of the ZONAX controller's seamless transition to PC control.
    • Establishment of a flexible platform for automating and managing cytometric experiments.

    Conclusions:

    • The developed interface provides a cost-effective and adaptable solution for controlling cytometric devices.
    • PC-based control significantly enhances the capabilities and user-friendliness of microscopy systems.
    • This approach facilitates advanced research by enabling precise automation and data management in cytometric applications.