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Updated: May 21, 2026
07:57
Viscoelastic Characterization of Soft Tissue-Mimicking Gelatin Phantoms using Indentation and Magnetic Resonance Elastography
Published on: May 10, 2022
Characterizing the elastic properties of tissues.
Riaz Akhtar1, Michael J Sherratt, J Kennedy Cruickshank
1School of Materials, The University of Manchester, Grosvenor Street, Manchester, M1 7HS, UK.
Materials Today (Kidlington, England)
|June 23, 2012
Summary
Aging affects the mechanical properties of biological tissues, impacting health and lifespan. This review examines age-related changes in artery mechanics using various techniques.
Area of Science:
- Biomedical Engineering
- Cardiovascular Science
- Gerontology
Background:
- Age-related changes in tissue mechanics significantly impact quality of life and mortality.
- Soft tissue mechanical properties are intrinsically linked to their complex microstructure.
- Understanding these microstructural changes is key to addressing age-related tissue degradation.
Purpose of the Study:
- To review age-related changes in the mechanical properties of arteries.
- To discuss in vivo and ex vivo techniques for assessing arterial mechanical changes.
- To highlight the link between tissue microstructure and age-related functional decline.
Main Methods:
- Review of existing literature on arterial mechanics and aging.
- Discussion of in vivo imaging and testing methodologies.
- Analysis of ex vivo biomechanical testing approaches.
Main Results:
- Arterial mechanical properties undergo significant age-related alterations.
- Microstructural changes in arterial tissue components drive these mechanical shifts.
- Various techniques provide insights into these dynamic changes.
Conclusions:
- Age-related changes in arterial mechanical properties are critical for cardiovascular health.
- Microstructural analysis is essential for understanding tissue behavior.
- Further research using discussed techniques can inform interventions for age-related cardiovascular conditions.
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