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Published on: October 12, 2012
Amoxicillin/clavulanic acid-induced pemphigus vulgaris: case report
Adone Baroni1, Teresa Russo, Franco Faccenda
1Department of Dermatology and Venereology, Second University of Naples, Naples, Italy. adone.baroni@gmail.com
Abstract:
Drug-induced pemphigus is a well-established variety of pemphigus, presenting with clinical and histopathologic features identical to idiopathic form. Medical history plays a fundamental role in the diagnosis of drug-induced pemphigus. A large variety of drugs have been implicated in its pathogenesis and they may induce acantholysis via biochemical and/or immune mechanism. We present a case of a 69-year-old woman affected by amoxicillin/clavulanic acid-induced pemphigus and discuss its pathogenetic mechanism.
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