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Magnetic resonance imaging-based treatment planning for prostate brachytherapy
Jeffrey M Albert1, David A Swanson, Thomas J Pugh
1Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
Brachytherapy
|June 26, 2012
Summary
Standard body array coil MRI (sMRI) offers advantages for prostate brachytherapy planning over transrectal ultrasound (TRUS) and endorectal coil MRI (erMRI). sMRI provides better soft-tissue delineation without the distortions seen with erMRI.
Area of Science:
- Urology
- Medical Imaging
- Radiation Oncology
Background:
- Transrectal ultrasound (TRUS) is the standard for prostate brachytherapy planning.
- Magnetic resonance imaging (MRI) offers superior anatomic detail compared to TRUS.
Purpose of the Study:
- To compare prostate brachytherapy treatment plans generated using TRUS, endorectal coil MRI (erMRI), and standard body array coil MRI (sMRI).
Main Methods:
- Retrospective analysis of treatment plans from 20 patients undergoing permanent seed brachytherapy.
- Re-planning treatments using sMRI and erMRI images by blinded investigators.
- Comparison of prostate volume, radioactivity-to-volume ratio, and dosimetric parameters.
Main Results:
- Endorectal coil MRI (erMRI) demonstrated anatomic distortions compared to TRUS.
- Standard MRI (sMRI) plans showed a 7.5% lower activity per volume than TRUS plans.
- sMRI plans achieved similar planning target volume coverage and improved dose homogeneity.
Conclusions:
- Endorectal coil MRI is not recommended for routine treatment planning due to distortions.
- Standard body array coil MRI may offer advantages for prostate brachytherapy planning due to superior soft-tissue visualization.
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