Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Cell-Matrix Interactions01:24

Overview of Cell-Matrix Interactions

The extracellular matrix or ECM holds cells together to form a tissue and allows the cells within the tissue to communicate. ECM comprises proteins such as fibronectin, collagen, laminin, etc. The most abundant protein in this space is collagen. Collagen fibers are interwoven with carbohydrate-containing protein molecules called proteoglycans. ECM allows cell migration and provides a structural scaffold at cell adhesion that anchors the cell when the extracellular matrix proteins interact with...
Cell-matrix's Response to Mechanical Forces01:13

Cell-matrix's Response to Mechanical Forces

In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals from the outside of the cell to the inside. The extracellular matrix is extensive, and its composition varies between different types of tissues. For example, the reticular fibers and ground substance make up the ECM in loose connective tissue, while collagen and bone minerals make up the ECM of bone tissue. 
Anchoring junctions mechanically attach a cell to the...
Interfacial Electrochemical Methods: Overview01:06

Interfacial Electrochemical Methods: Overview

Interfacial electrochemical methods focus on the phenomena occurring at the boundary between an electrode and a solution, as opposed to bulk methods that concentrate on the solution's overall properties. These interfacial methods are classified as either static or dynamic based on the presence of a nonzero current in the electrochemical cell and the consistency of analyte concentrations. Static methods, such as potentiometry, measure the cell's potential without any significant current passing...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Regulation of olfactory chloride and cyclic nucleotide-gated channels by cholesterol.

The Journal of general physiology·2026
Same author

Repulsive Gas-Electrode van der Waals Forces Enable Charge Transfer Reactions under Chemically Modified Bubbles.

Journal of the American Chemical Society·2026
Same author

Hair-raising: how carbon contamination can drive static charging.

Nature·2026
Same author

A Facile Electrochemical Approach to Synthesizing Stable Single Metal Atom Catalytic Centers and Clusters on N-Doped Carbon for Electrocatalysis.

Small (Weinheim an der Bergstrasse, Germany)·2025
Same author

Metal-Enhanced Fluorescence via Spacer-Free and Electrogenerated Nanomaterials at Oil-Fouled Electrodes.

Langmuir : the ACS journal of surfaces and colloids·2025
Same author

A biofabricated 3D cancer-stroma tumor microenvironment model.

Biofabrication·2025

Related Experiment Video

Updated: May 21, 2026

Revealing Electromechanical Control of Tissue Homeostasis Using a Two-Layer Microfluidic Device
11:08

Revealing Electromechanical Control of Tissue Homeostasis Using a Two-Layer Microfluidic Device

Published on: September 19, 2025

Using an electrical potential to reversibly switch surfaces between two states for dynamically controlling cell

Cheuk Chi Albert Ng1, Astrid Magenau, Siti Hawa Ngalim

  • 1School of Chemistry and Australian Centre for NanoMedicine, The University of New South Wales, Sydney NSW 2052, Australia.

Angewandte Chemie (International Ed. in English)
|June 26, 2012
PubMed
Summary

Researchers developed smart surfaces that control cell adhesion. Applying electrical potentials switches the accessibility of cell-attracting peptides, enabling dynamic surface functionality for advanced biomaterials.

More Related Videos

Patterning Cells on Optically Transparent Indium Tin Oxide Electrodes
26:16

Patterning Cells on Optically Transparent Indium Tin Oxide Electrodes

Published on: August 20, 2007

Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads
07:55

Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads

Published on: March 8, 2017

Related Experiment Videos

Last Updated: May 21, 2026

Revealing Electromechanical Control of Tissue Homeostasis Using a Two-Layer Microfluidic Device
11:08

Revealing Electromechanical Control of Tissue Homeostasis Using a Two-Layer Microfluidic Device

Published on: September 19, 2025

Patterning Cells on Optically Transparent Indium Tin Oxide Electrodes
26:16

Patterning Cells on Optically Transparent Indium Tin Oxide Electrodes

Published on: August 20, 2007

Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads
07:55

Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads

Published on: March 8, 2017

Area of Science:

  • Biomaterials science
  • Surface chemistry
  • Cellular engineering

Background:

  • Controlling cell adhesion is crucial for biomedical applications.
  • Existing methods for dynamic surface control are limited.

Purpose of the Study:

  • To engineer smart surfaces with switchable cell adhesion properties.
  • To investigate the effect of electrical potentials on RGD peptide accessibility.

Main Methods:

  • Fabrication of surfaces functionalized with antifouling and RGD peptide-terminated molecules.
  • Characterization of surface properties.
  • Application of electrical potentials (+300 mV or -300 mV) to modulate surface behavior.

Main Results:

  • Successfully fabricated switchable surfaces.
  • Demonstrated dynamic control over RGD peptide accessibility.
  • Showcased the ability to reversibly control cell adhesion through electrical stimulation.

Conclusions:

  • Developed a novel approach for creating dynamically tunable cell-adhesive surfaces.
  • Electrostatic control offers a promising strategy for advanced biomaterial design.
  • Potential applications in tissue engineering, biosensing, and regenerative medicine.