Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 21, 2026

Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy
12:26

Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy

Published on: January 29, 2022

Rigidity guided cell attachment on inkjet-printed patterns.

Ying-Chih Liao1, Yun-Ting Ma, Chi-Hui Huang

  • 1Department of Chemical Engineering, ‡Department of Mechanical Engineering, National Taiwan University, Taipei, Taiwan.

ACS Applied Materials & Interfaces
|June 27, 2012
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Engineering Composite of Silver Nanoparticles/Skim Natural Rubber/Bacterial Cellulose and Its Potential Application for a Humidity Sensing Device.

ACS omega·2026
Same author

Sustainable AuNPs@GO Paper-Based SERS Platform with Integrated Chromatography for Point-of-Care Environmental Sensing.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2026
Same author

Biomimetic Hydrogels with Oxidative Cross-Linking for Ionically Conductive Interfaces in Long-Term Wearable Bioelectronics.

Biomacromolecules·2026
Same author

Sustained ocular drug delivery via polydopamine chitosan curcumin nanocomposite coatings.

Discover nano·2026
Same author

Engineering Functional PVA: A Comprehensive Review of Chemical Modifications and Prospective Developments.

ACS polymers Au·2026
Same author

Photocurable Nanocellulose-Based Hydrogel for Real-Time Electrochemical Sweat Monitoring in Smart Textiles.

Langmuir : the ACS journal of surfaces and colloids·2025

Researchers developed a novel method using inkjet-printed polylactic acid (PLA) on alginate films to control cell attachment. Fibroblast cells preferentially adhered to more rigid PLA surfaces, enabling patterned cell growth on biodegradable materials.

Area of Science:

  • Biomaterials Science
  • Cell Biology
  • Surface Engineering

Background:

  • Controlling cell attachment and patterning is crucial for tissue engineering and regenerative medicine.
  • Biocompatible substrates with tunable properties are needed to guide cellular behavior.
  • Current methods for creating patterned cell adhesion can be complex and limited.

Purpose of the Study:

  • To present a new methodology for controlling fibroblast cell attachment on composite biocompatible surfaces.
  • To investigate the influence of surface rigidity variations on cell adhesion.
  • To demonstrate the fabrication of patterned cell growth using inkjet printing.

Main Methods:

  • Inkjet printing of multiple polylactic acid (PLA) layers onto dry alginate films to create composite surfaces.

More Related Videos

Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells
10:14

Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells

Published on: November 18, 2016

Creating Transient Cell Membrane Pores Using a Standard Inkjet Printer
07:07

Creating Transient Cell Membrane Pores Using a Standard Inkjet Printer

Published on: March 16, 2012

Related Experiment Videos

Last Updated: May 21, 2026

Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy
12:26

Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy

Published on: January 29, 2022

Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells
10:14

Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells

Published on: November 18, 2016

Creating Transient Cell Membrane Pores Using a Standard Inkjet Printer
07:07

Creating Transient Cell Membrane Pores Using a Standard Inkjet Printer

Published on: March 16, 2012

  • Fabrication of surfaces with controlled rigidity gradients.
  • Culturing of fibroblast 3T3-L1 cells on the fabricated composite films in cell culture medium.

    • Main Results:

    • Fibroblast 3T3-L1 cells exhibited preferential adhesion to polylactic acid (PLA) surfaces with higher rigidity.
    • The inkjet printing approach successfully created defined patterns of cell attachment.
    • Composite surfaces with tunable rigidity were achieved.

    Conclusions:

    • A novel and effective method for controlling cell adhesion and patterning on biodegradable substrates was established.
    • Surface rigidity is a key factor influencing fibroblast cell attachment.
    • This technique offers a versatile platform for fabricating engineered biological matrices.