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Updated: May 21, 2026

Clinical Imaging of Microwave Mammography
Published on: November 14, 2025
Incidental pleural effusions detected on screening breast MRI
Jonathan Nguyen1, Brandi T Nicholson, James T Patrie
1Department of Radiology, Tufts Medical Center, Boston, MA, USA.
Physiologic pleural effusions are common in women undergoing screening breast MRI. Reference ranges are up to 7 mm on the right and 5 mm on the left, and these findings do not require further investigation.
Area of Science:
- Radiology
- Oncology
- Thoracic Medicine
Background:
- Pleural effusions are a frequent complication of malignancy.
- Differentiating malignant from physiologic effusions on breast MRI is crucial.
- Physiologic effusions can be mistaken for pathological findings.
Purpose of the Study:
- To determine the incidence of physiologic pleural effusions in healthy women.
- To establish reference ranges for these effusions on screening breast MRI.
- To aid in the accurate interpretation of breast MRI findings.
Main Methods:
- Retrospective analysis of 200 women undergoing screening breast MRI.
- Exclusion of patients with malignancy, prior cancer, or cardiac/pulmonary disease.
- Measurement of pleural effusion size and laterality.
Main Results:
- 87% of healthy women had pleural effusions; 62% were bilateral.
- Right-sided effusions were more frequent (81.5%) and slightly larger (mean 3.3 mm) than left-sided (67.5%, mean 2.8 mm).
- Reference ranges established: up to 7 mm on the right, 5 mm on the left.
Conclusions:
- Small pleural effusions are common physiologic findings in screening breast MRI.
- These findings in healthy women should not warrant further diagnostic testing.
- Understanding these normal variations improves diagnostic accuracy and reduces unnecessary procedures.
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