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Female sexual dysfunction in type 2 diabetes: a case control study
Farzaneh Sharifiaghdas1, Mohaddeseh Azadvari, Nasser Shakhssalim
1Shahid Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. fsharifiaghdas @ yahoo.com
Summary
Women with type 2 diabetes mellitus experience higher rates of sexual dysfunction, particularly in desire, arousal sensation, and pain. Further research is needed to confirm these findings in larger patient populations.
Area of Science:
- Endocrinology
- Sexual Medicine
- Reproductive Health
Background:
- Type 2 diabetes mellitus (T2DM) is a chronic condition affecting millions globally.
- T2DM is associated with various complications, including microvascular and macrovascular issues.
- Female sexual dysfunction (FSD) is a prevalent condition impacting quality of life.
Purpose of the Study:
- To investigate the prevalence and characteristics of sexual dysfunction in women with T2DM.
- To compare sexual function in women with T2DM to non-diabetic controls.
- To identify specific domains of sexual function most affected by T2DM.
Main Methods:
- A comparative study involving 45 women with T2DM and 91 non-diabetic controls.
- Participants were married, non-menopausal women aged 20-55 years.
- Sexual function assessed using a validated questionnaire; genitourinary, ophthalmologic, and neurologic examinations performed; relevant blood tests conducted.
Main Results:
- Women with T2DM exhibited significantly higher probabilities of FSD in desire (71.1% vs 56.6%), arousal sensation (84.4% vs 67.0%), and pain (8.9% vs 25.3%) compared to controls.
- While overall FSD prevalence was high in both groups, specific domains showed statistically significant differences.
- Diabetic retinopathy was observed in 12.5% of T2DM patients; deep tendon reflexes were normal in all participants.
Conclusions:
- Sexual dysfunction is highly prevalent in women with T2DM, affecting multiple domains.
- Significant differences in desire, arousal sensation, and pain were noted between diabetic and non-diabetic women.
- Larger-scale studies are recommended to validate these findings and explore underlying mechanisms.
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