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[Prevalence of neurological disorders among children with Down syndrome]

Beatriz Gaete1, Cecilia Mellado, Marta Hernández

  • 1División de Pediatría, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Revista Medica De Chile
|June 29, 2012
PubMed

Insights

Neurological disorders affect nearly 40% of children with Down syndrome (DS). Ocular motor issues and epilepsy are the most frequent conditions observed in this population.

Area of Science:

  • Pediatric Neurology
  • Genetics
  • Developmental Disorders

Context:

  • Neurological disturbances are frequently observed in children with Down syndrome (DS).
  • Understanding the prevalence of these disorders is crucial for early intervention and management.
  • DS affects approximately 1 in 700 live births, with a range of associated health conditions.

Purpose:

  • To determine the prevalence of neurological disorders in children with Down syndrome.
  • To identify the most common types of neurological conditions affecting this population.

Summary:

  • A review of medical records for 253 children with DS (aged 1 day to 23 years) was conducted.
  • The overall prevalence of neurological disorders was found to be 38.7%.
  • Ocular motor disorders (26%) and epilepsy (12%) were the most prevalent neurological issues identified.

Impact:

  • Neurological disorders are significantly more common in children with DS compared to the general pediatric population.
  • Early identification of ocular motor disorders and epilepsy in children with DS can lead to timely interventions.
  • This study highlights the importance of routine neurological screening for children diagnosed with Down syndrome.
Abstract

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