Oligodendroglial process formation is differentially affected by modulating the intra- and extracellular cholesterol

Matthias Schmitz1, Sandra C Signore, Inga Zerr

  • 1Max-Planck Institute of Experimental Medicine, RU Neural Regeneration, Hermann-Rein-Straße 3, 37075, Goettingen, Germany. matthias.schmitz@med.uni-goettingen.de

Summary

Caveolin-1 influences cholesterol trafficking in oligodendrocytes (OL). Modulating cholesterol levels impacts OL process formation and nerve growth factor (NGF) signaling, suggesting NPC1L1

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