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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Enterobacter amnigenus endophthalmitis.

Corey Westerfeld1, George N Papaliodis, Irmgard Behlau

  • 1From the *Department of Ophthalmology, Massachusetts Eye and Ear Infirmary; and †Department of Infectious Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Retinal Cases & Brief Reports
|June 29, 2012
PubMed
Summary
This summary is machine-generated.

A rare case of Enterobacter amnigenus endophthalmitis in a healthy individual was successfully treated with antibiotics. This study highlights effective management for this unusual bacterial eye infection, leading to good visual recovery.

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Endophthalmitis is a serious intraocular infection.
  • Enterobacter species are uncommon causes of endophthalmitis.
  • Enterobacter amnigenus is rarely pathogenic, particularly in healthy individuals.

Purpose of the Study:

  • To report a case of Enterobacter amnigenus endophthalmitis.
  • To describe the clinical presentation and management of this rare infection.
  • To emphasize the potential for good visual outcomes with prompt treatment.

Main Methods:

  • A 33-year-old immunocompetent male presented with unilateral hypopyon uveitis and severely reduced vision.
  • Vitreous cultures were essential for identifying Enterobacter amnigenus as the causative agent.
  • Treatment involved a combination of intravenous and intravitreal antibiotics.

Main Results:

  • The patient experienced a significant improvement in visual acuity following antibiotic therapy.
  • Final visual acuity in the affected eye was restored to 20/30.
  • The patient demonstrated a favorable response to the prescribed treatment regimen.

Conclusions:

  • Enterobacter amnigenus endophthalmitis, though rare, can occur in immunocompetent individuals.
  • Prompt and appropriate antibiotic treatment is crucial for achieving successful visual recovery.
  • This case broadens the understanding of Enterobacter amnigenus pathogenicity and endophthalmitis management.