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Variations in the size of focal nodular hyperplasia on magnetic resonance imaging

C Ramírez-Fuentes1, L Martí-Bonmatí, A Torregrosa

  • 1Servicio de Radiología, Hospital de Manises, Valencia, España.

Radiologia
|June 30, 2012
PubMed
Abstract

Insights

Focal nodular hyperplasia (FNH) size changes are common during long-term magnetic resonance imaging (MRI) follow-up. These variations, observed in 20% of lesions, do not typically alter the diagnosis and appear unrelated to hormonal factors.

Area of Science:

  • Hepatobiliary Imaging
  • Gastrointestinal Radiology
  • Abdominal Imaging

Background:

  • Focal nodular hyperplasia (FNH) is a benign liver lesion.
  • Long-term imaging characteristics of FNH require further elucidation.

Purpose of the Study:

  • To evaluate changes in the size of focal nodular hyperplasia (FNH) during long-term magnetic resonance imaging (MRI) follow-up.
  • To determine if hormonal factors influence FNH size variations.

Main Methods:

  • Retrospective review of 44 FNHs in 30 patients with serial MRI studies (≥12 months apart).
  • Measurement of lesion diameter and calculation of percentage variation.
  • Analysis of predisposing hormonal factors (pregnancy, menopause, oral contraceptives, corticoids).

Main Results:

  • Mean follow-up interval was 35 months.
  • 80% of FNH lesions remained stable in size.
  • 20% of lesions exhibited significant size variation (≥20%), with 16% decreasing and 4% increasing.

Conclusions:

  • Size variations in FNH during MRI follow-up are relatively common.
  • Observed size changes do not necessitate a change in diagnosis.
  • FNH size variations appear independent of hormonal influences.
Keywords:
Anticonceptivos orales<Birth control pills<Focal nodular hyperplasiaFollow-upHiperplasia nodular focalHistoria naturalLiver magnetic resonance imagingNatural historyResonancia magnética hepáticaSeguimiento

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