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Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
Advanced transitional cell carcinoma of the bladder in a 16-year-old girl with Hinman syndrome
Anas I Ghousheh1, Charles T Durkee, Travis W Groth
1Department of Pediatric Urology, Medical College of Wisconsin, Milwaukee, WI 53226, USA. aghousheh@chw.org
Abstract:
The present report describes a 16-year-old girl with a history of Hinman syndrome who was found to have invasive transitional cell carcinoma of the bladder. Bladder cancer is rare in children. Typically, the tumors are of low grade and stage. We present the first case of a teenage girl diagnosed with Hinman syndrome who developed an invasive bladder transitional cell carcinoma. The patient with a neurogenic bladder who has undergone bladder augmentation is at increased risk for bladder cancer. This risk may now have to be extended out to the non-neurogenic neurogenic bladder population if further cases are identified.
