Reactive lymphoid hyperplasia of lacrimal canaliculus caused by a silicone plug

Complications of tumorigenesis by a lacrimal silicone plug are rarely reported and most of them were cases of granuloma due to chronic inflammation. The authors present a case of a 57-year-old healthy woman complaining of lower eyelid swelling and protruding mass from lower punctum who had undergone insertion of a lacrimal silicone plug. Surgical mass resection was performed and initial histopathology revealed lymphoid hyperplasia. Additional immunophenotypic markers CD3, CD20, and BCL2 showed reactive lymphoid hyperplasia. It has a histopathologic significance in that it can mimic lymphoma and should be distinguished from malignancy.