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Updated: May 20, 2026

A Patient-Derived Xenograft Model for Venous Malformation
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Subungual glomangiomyoma - a case report.

Adi Wollstein1, Ronit Wollstein

  • 1Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

Hand Surgery : an International Journal Devoted to Hand and Upper Limb Surgery and Related Research : Journal of the Asia-Pacific Federation of Societies for Surgery of the Hand
|June 30, 2012
PubMed
Summary

Glomus tumors, rare glomangiomyomas, may present without typical symptoms, suggesting histology is key. This case highlights a subungual glomangiomyoma with a favorable outcome.

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Area of Science:

  • Oncology
  • Dermatopathology
  • Surgical Pathology

Background:

  • Glomus tumors are benign neoplasms originating from glomus bodies.
  • They commonly occur in the nail bed, presenting with pain and temperature sensitivity.
  • Glomangiomyomas, a rare subtype, are characterized by abundant smooth muscle.

Observation:

  • A patient presented with a subungual glomangiomyoma, an unusual location for this subtype.
  • The tumor lacked the typical symptoms of point and temperature sensitivity.
  • Surgical excision resulted in a favorable outcome.

Findings:

  • This case suggests histological subtype may influence clinical presentation more than anatomical location.
  • Subungual glomangiomyomas can occur without classic glomus tumor symptoms.

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  • Histological classification is crucial for understanding glomus tumor behavior.
  • Implications:

    • Clinical presentation of glomus tumors may not always align with anatomical location.
    • Consider glomangiomyoma in the differential diagnosis of subungual masses, even without typical symptoms.
    • Further research into the correlation between glomus tumor histology and clinical presentation is warranted.