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Subependymoma: clinical features and surgical outcomes
Amit Jain1, Anubhav G Amin, Punya Jain
1Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD, USA. amitjain012@gmail.com
Neurological Research
|July 4, 2012
Summary
Subependymomas are rare, slow-growing tumors. Surgical removal offers long-term symptom relief and tumor control, with no recurrence observed in this study.
Area of Science:
- Neurosurgery
- Neuropathology
- Oncology
Background:
- Subependymomas are uncommon, benign tumors originating in the central nervous system.
- This study aims to detail the clinical, radiological, and surgical outcomes for subependymomas.
Observation:
- Fifteen patients had fourth ventricle tumors, six had lateral ventricle tumors, and five had spinal tumors.
- Common symptoms included headaches, vision changes, and balance issues.
- Tumors displayed characteristic imaging features on MRI, including heterogeneous enhancement and signal intensity variations.
Findings:
- Maximal safe resection provided symptomatic relief and long-term tumor control without recurrence in all patients.
- Surgical approaches varied by tumor location, utilizing microsurgical techniques.
- Tumor location did not correlate with patient age, resection extent, or complication development.
Implications:
- Subependymomas can cause cerebrospinal fluid (CSF) obstruction or myelopathy.
- Symptomatic subependymomas warrant surgical intervention for long-term control.
- Maximal safe resection is an effective strategy for managing these indolent neoplasms.
