Related Experiment Video
Updated: May 20, 2026

DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat (VNTR) - Fragment Length Analysis (FLA)
Published on: July 15, 2011
LSHGD: a database for human leprosy susceptible genes
C George Priya Doss1, N Nagasundaram, Jain Srajan
1Medical Biotechnology Division, School of Biosciences and Technology, Center for Nanobiotechnology, VIT University, Vellore 632014, Tamil Nadu, India. georgecp77@yahoo.co.in
Researchers created the Leprosy Susceptible Human Gene Database (LSHGD) to study host genetics in leprosy. This database integrates genes and polymorphisms, aiding research into disease susceptibility and multi-drug resistance.
Area of Science:
- Genetics
- Immunology
- Infectious Diseases
Background:
- Host genetic factors influence susceptibility and response to Mycobacterium leprae infection.
- Understanding these genetic factors is crucial for leprosy research.
Purpose of the Study:
- To develop a comprehensive Leprosy Susceptible Human Gene Database (LSHGD).
- To create a user-friendly platform for exploring human genetic involvement in leprosy.
- To investigate genetic control over leprosy susceptibility and multi-drug resistance.
Main Methods:
- Conducted an extensive literature search to identify genes associated with leprosy.
- Integrated data on 45 leprosy-associated human genes into a database.
- Developed an interactive platform for accessing genetic information.
Main Results:
- The Leprosy Susceptible Human Gene Database (LSHGD) was established.
- The database includes information on associated genes, protein sequences, 3D structures, and polymorphisms.
- It allows users to retrieve specific genetic information related to leprosy.
Conclusions:
- LSHGD is the first human genetic database for leprosy.
- It serves as a valuable, multifunctional tool for researchers.
- The platform is freely accessible online to facilitate leprosy research.
More Related Videos
Related Concept Videos
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Human Genetics
The complex relationship between genetics and psychology is observable through common biological components such...
Non-LTR Retrotransposons
Single Nucleotide Polymorphisms-SNPs

