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Cerebral Hemispheres

Cerebral Hemispheres

The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...

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Related Experiment Video

Updated: May 20, 2026

Characterization of the Sense of Agency over the Actions of Neural-machine Interface-operated Prostheses

Characterization of the Sense of Agency over the Actions of Neural-machine Interface-operated Prostheses

Published on: January 7, 2019

A neurally-interfaced hand prosthesis tuned inter-hemispheric communication.

G Di Pino¹, C Porcaro, M Tombini

¹Department of Neurology, Campus Bio-Medico University, Rome, Italy.

Restorative Neurology and Neuroscience

|July 4, 2012

Summary

This summary is machine-generated.

Direct brain-prosthesis connection normalizes brain activity and connectivity in amputees. This restores sensorimotor function and reduces phantom limb symptoms by re-establishing neural pathways.

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Last Updated: May 20, 2026

Characterization of the Sense of Agency over the Actions of Neural-machine Interface-operated Prostheses

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A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study

Published on: November 6, 2015

Area of Science:

Neuroscience
Biomedical Engineering
Rehabilitation Medicine

Background:

Hand prostheses often fail due to poor interfacing.
Neural interfaces offer bidirectional communication for better control and sensation.
Previous studies show reduced cortical asymmetry and phantom limb symptoms with neural interfaces.

Observation:

This study investigated the impact of a direct bidirectional brain-hand prosthesis connection.
Electroencephalography (EEG) data was analyzed using Functional Source Separation (FSS).
FSS allows for the decomposition of data to access cortical patch activities.

Findings:

Bi-hemispheric cortices normalized in activity and functional connectivity during motor commands to the prosthesis.
The study observed normalization of topographical and spectral patterns in brain activity.
Functional connectivity between homologous hand-controlling areas improved.

Implications:

Re-establishing central-peripheral communication via neural interfaces promotes beneficial neural plasticity.
This reorganization benefits not only directly connected areas but also the balance of the bi-hemispheric system.
Improved functional balance aids in motor control for amputees using neurally-interfaced prostheses.