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Updated: May 20, 2026

Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)
10:02

Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)

Published on: March 12, 2020

Early markers in infants and toddlers for development of ADHD

Mina Gurevitz1, Ronny Geva, Maya Varon

  • 11Maccabi Health Services, Herzliya, Israel.

Journal of Attention Disorders
|July 4, 2012
PubMed

Insights

Identifying early risk factors for Attention Deficit Hyperactivity Disorder (ADHD) in infancy, such as maternal age and developmental delays, can aid in early intervention strategies for children.

Area of Science:

  • Pediatric neurology
  • Developmental psychology
  • Child psychiatry

Background:

  • Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmental disorder.
  • Early identification of risk factors is crucial for timely intervention.
  • Infancy and toddlerhood present a critical window for observing developmental trajectories.

Purpose of the Study:

  • To characterize risk factors for ADHD observable in infancy.
  • To identify early markers that may predict later ADHD diagnosis.
  • To inform potential early intervention strategies.

Main Methods:

  • Retrospective analysis of well-baby clinic records from birth to 18 months.
  • Comparison of 58 children diagnosed with ADHD later in life against 58 control children.
  • Statistical analysis to identify significant differences between groups.

Main Results:

  • Eight infant parameters significantly associated with ADHD: advanced maternal age, lower maternal education, family history of ADHD, social problems, decreased head circumference percentile, delayed motor and language development, and difficult temperament.
  • A predictive regression model explained 58% of the variance in ADHD development.
  • Specific risk markers identified at 0-1 months, 3-18 months, and 9-18 months.

Conclusions:

  • Early risk markers in infancy and toddlerhood can predict ADHD development.
  • Findings highlight the importance of monitoring developmental milestones and environmental factors.
  • This research supports the potential for early screening and intervention in at-risk infants.
Abstract

Keywords:
ADHDearly markers in infancy

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