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Suspension Culture Production and Purification of Adeno-Associated Virus by Iodixanol Density Gradient Centrifugation for In Vivo Applications
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Suspension Culture Production and Purification of Adeno-Associated Virus by Iodixanol Density Gradient Centrifugation for In Vivo Applications

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Purification and concentration of alphavirus

Kenneth Lundstrom

    Cold Spring Harbor Protocols
    |July 4, 2012
    PubMed
    Summary

    Alphaviral vectors offer efficient gene delivery for research and therapy, but require purification for optimal use. This protocol details three methods to concentrate and purify alphaviruses, improving cell survival and enabling clinical applications.

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