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Drug Toxicity: Dose-Dependent Reactions01:24

Drug Toxicity: Dose-Dependent Reactions

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Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
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Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity
09:52

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Published on: March 16, 2018

Ototoxicity: the hidden menace.

Manisha Bisht, S S Bist

    Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
    |July 4, 2012
    PubMed
    Summary
    This summary is machine-generated.

    Otolaryngologists must recognize drug-induced otological side effects. This review consolidates commonly used medications with potential hearing and balance issues, aiding in diagnosis and treatment.

    Keywords:
    Hearing lossOtotoxic drugsOtotoxicity

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    Area of Science:

    • Otolaryngology
    • Pharmacology

    Background:

    • Otolaryngology encompasses medical management of diseases beyond surgical interventions.
    • Understanding drug treatments and their side effects is crucial for otolaryngologists.
    • Identifying medication-induced symptoms can lead to simple, effective remedies.

    Purpose of the Study:

    • To compile a comprehensive list of commonly used drugs that can cause otological side effects.
    • To raise awareness among otolaryngologists about less common drug-induced ototoxicity.

    Main Methods:

    • Literature review and consolidation of known ototoxic medications.
    • Categorization of drugs based on their otological side effect profiles.

    Main Results:

    • Identification of numerous commonly prescribed drugs with potential otological side effects.
    • Highlighting the importance of considering medication history in ENT symptom evaluation.

    Conclusions:

    • Otolaryngologists require thorough knowledge of drug-induced otological adverse events.
    • Awareness and recognition of these side effects can significantly improve patient management and outcomes.