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[Primary peptic ulcer in infancy and childhood. Personal experience]
R Lama Moré1, G Prieto Bozano, S Carrasco Gandía
1Unidad de Gastroenterología y Nutrición, Hospital Infantil La Paz, Madrid.
Insights
Peptic ulcer disease in children is increasingly diagnosed. Campylobacter pylori infection is linked to recurrent abdominal pain in pediatric patients.
Area of Science:
- Pediatric Gastroenterology
- Infectious Diseases
Context:
- Primary peptic ulcer disease in children is a significant clinical concern.
- Diagnostic methods include endoscopy and radiological studies.
- Increasing endoscopy rates correlate with higher detection of peptic ulcer disease.
Purpose:
- To review primary peptic ulcer disease in a pediatric cohort.
- To investigate the prevalence of Campylobacter pylori infection.
- To analyze clinical presentation and outcomes based on age and infection status.
Summary:
- A retrospective review of 61 children with peptic ulcer disease was conducted.
- Campylobacter pylori was identified in 50% of patients tested (10/20).
- Gastrointestinal bleeding was more common in younger children, while abdominal pain predominated in older children. Patients with cystic fibrosis showed poorer treatment response.
Impact:
- Highlights the association between Campylobacter pylori and recurrent abdominal pain in children.
- Underscores the importance of endoscopic evaluation and testing for H. pylori in pediatric peptic ulcer disease.
- Identifies specific patient groups, like those with cystic fibrosis, who may require tailored management strategies.
Abstract:
We report a retrospective review of primary peptic ulcer peptic disease in 61 children. The follow-up period ranged from 1 month to 6 years. All cases were confirmed by endoscopic examination and related with radiological studies result. The number of ulcer peptic disease detected increased as much as the number of endoscopies were performed annually. In the last 20 patients pinch biopsies from antrum were taken looking for Campylobacter pylori, encountering 10 positives. The relation male:female were 2:1. Gastrointestinal bleeding had occurred in children below 6 years and abdominal pain was seen in older children. All of patients who had C. pylory infection had had recurrent abdominal pain. Three peptic ulcer were documented in patients with cystic fibrosis, which had the worse response to medical treatment. Others, had a satisfactory response.